Adrenergic beta-receptor sensitivity in essential tremor.
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چکیده
منابع مشابه
Adrenergic beta-receptor sensitivity in essential tremor.
Adrenergic beta-receptor sensitivity of six male patients with essential tremor and six age-matched normal controls was assessed by measuring the response in the heart rate and postural tremor to incremental injections of the adrenergic beta-agonist isoprenaline. The relative increase in heart rate and tremor in essential tremor patients did not differ from that in normal controls. It is conclu...
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A double blind trial of a single 40 mg dose of the beta adrenergic blocking agent propranolol in the treatment of essential tremor produced significant reduction of tremor in four of five patients, but this effect was transient and had considerably diminished within four hours. A month's double blind clinical trial of propranolol, in a dose of 30 mg three times a day, showed that the active dru...
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The beta-2 adrenergic receptor (β2 adrenoreceptor), also known as ADRB2, is a cell membrane-spanning beta-adrenergic receptor that interacts with (binds) epinephrine, a hormone and neurotransmitter (ligand synonym, adrenaline) whose signaling, via a downstream Ltype calcium channel interaction, mediates physiologic responses such as smooth muscle relaxation and bronchodilation. Unlike other adr...
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Address reprint requests to Dr. Galant, Memorial Hospital Medical Center of Long Beach, Calif. Received for publication 12 August 1980 and in revised form 23 March 1981. group to include agonist binding, receptor-adenylate cyclase coupling, intrinsic adenylate cyclase activity, and catecholamine metabolism may help determine the basic cause of beta adrenergic hyporesponsiveness in both CFH and CF.
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Coherence between the bioelectric activity of sensorimotor cortex and contralateral muscles can be observed around 20 Hz. By contrast, physiological tremor has a dominant frequency around 10 Hz. Although tremor has multiple sources, it is partly central in origin, reflecting a component of motoneuron discharge at this frequency. The motoneuron response to ~20 Hz descending input could be altere...
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ژورنال
عنوان ژورنال: Journal of Neurology, Neurosurgery & Psychiatry
سال: 1984
ISSN: 0022-3050
DOI: 10.1136/jnnp.47.11.1216